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Endocrine Abstracts

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ea0038ja1 | Society for Endocrinology Journal Award ‐ <emphasis role="italic">Journal of Endocrinology</emphasis> | SFEBES2015

Potential biomarker of metformin action

He Ling , Meng Shumei , Germain-Lee Emily L , Radovick Sally , Wondisford Fredric E

Journal of Endocrinology 2014 221 363–369. DOI: 10.1530/JOE-14-0084...
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ea0099rc9.3 | Rapid Communications 9: Pituitary and Neuroendocrinology | Part II | ECE2024

Identifying potential small molecule “metabolites” as biomarkers for growth hormone deficiency (GHD): Insights from a novel mouse model

Al-Samerria Sarmed , Xu Huiting , Phelan Joseph , Diaz Rubio Maria Elena , Yamada Sayaka , Negron Ariel , Wondisford Fredric , Radovick Sally

Growth hormone deficiency (GHD) diagnosis poses a significant challenge since no test definitively diagnoses GHD. The current diagnostic approach for GHD relies on a determination of auxologic parameters followed by determining Growth Hormone (GH) levels and Insulin-like Growth Factor-I (IGF-I) in serum. However, clinical assessment and interpretation of GH and IGF-1 levels lack sensitivity. Further provocative studies of GH secretion do not have a precise cutoff level that di...
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ea0099p125 | Pituitary and Neuroendocrinology | ECE2024

Consensus and controversies on the diagnosis of GH-deficiency in children and adults - A Delphi survey by the GH research society

C. Arlien-Soborg Mai , Radovick Sally , Cristina da Silva Boguszewski Margaret , Bidlingmaier Martin , Johannsson Gudmundur , R. Hoffman Andrew , Otto Jorgensen Jens

Background: Growth hormone deficiency (GHD) is a rare disorder characterized by pronounced and symptomatic hypo secretion of growth hormone (GH) from the anterior pituitary gland. Biochemical tests are used as part of the diagnosis in both children and adults but controversies remain as regards whom, when, and how to test, and also how to interpret a given biochemical test result.Aim: To map the current clinical practice of GHD diagnosing in children and...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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